2yvv: Difference between revisions

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New page: left|200px<br /><applet load="2yvv" size="350" color="white" frame="true" align="right" spinBox="true" caption="2yvv, resolution 2.60Å" /> '''Crystal structure of...
 
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[[Image:2yvv.jpg|left|200px]]<br /><applet load="2yvv" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2yvv, resolution 2.60&Aring;" />
'''Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites'''<br />


==About this Structure==
==Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites==
2YVV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes] with <scene name='pdbligand=LBT:'>LBT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Hyaluronate_lyase Hyaluronate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.2.1 4.2.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVV OCA].  
<StructureSection load='2yvv' size='340' side='right'caption='[[2yvv]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
[[Category: Hyaluronate lyase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2yvv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YVV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900008:alpha-lactose'>PRD_900008</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yvv OCA], [https://pdbe.org/2yvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yvv RCSB], [https://www.ebi.ac.uk/pdbsum/2yvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yvv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9A0M7_STRP1 Q9A0M7_STRP1]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yv/2yvv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yvv ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Hyaluronidase 3D structures|Hyaluronidase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptococcus pyogenes]]
[[Category: Streptococcus pyogenes]]
[[Category: Betzel, C.]]
[[Category: Betzel C]]
[[Category: Bhakuni, V.]]
[[Category: Bhakuni V]]
[[Category: Kaur, P.]]
[[Category: Kaur P]]
[[Category: Kumar, R.Prem.]]
[[Category: Mishra P]]
[[Category: Mishra, P.]]
[[Category: Perbandt M]]
[[Category: Perbandt, M.]]
[[Category: Prem Kumar R]]
[[Category: Sharma, S.]]
[[Category: Sharma S]]
[[Category: Singh, N.]]
[[Category: Singh N]]
[[Category: Singh, T.P.]]
[[Category: Singh TP]]
[[Category: LBT]]
[[Category: complex]]
[[Category: hyaluronan lyase]]
[[Category: hyaluronidase]]
[[Category: lactose]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 15:29:36 2008''

Latest revision as of 09:06, 25 October 2023

Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites

2yvv, resolution 2.60Å

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