3rgk: Difference between revisions

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[[Image:3rgk.jpg|left|200px]]


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==Crystal Structure of Human Myoglobin Mutant K45R==
The line below this paragraph, containing "STRUCTURE_3rgk", creates the "Structure Box" on the page.
<StructureSection load='3rgk' size='340' side='right'caption='[[3rgk]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3rgk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RGK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RGK FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3rgk|  PDB=3rgk  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rgk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rgk OCA], [https://pdbe.org/3rgk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rgk RCSB], [https://www.ebi.ac.uk/pdbsum/3rgk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rgk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYG_HUMAN MYG_HUMAN] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We have grown crystals in trigonal space group P3(2)21 of a mutant human myoglobin, aquomet form, in which lysine at position 45 has been replaced by arginine and cysteine at position 110 has been replaced by alanine. Suitable crystals of native recombinant human myoglobin have not been obtained. We have used the molecular replacement method to determine the X-ray crystal structure of the mutant at 2.8 A resolution. At the present stage of refinement, the crystallographic R-value for the model, with tightly restrained stereochemistry, is 0.158 for 5.0 to 2.8 A data. As expected, the overall structure is quite similar to the sperm whale myoglobin structure. Arginine 45 adopts a well-ordered conformation similar to that found in aquomet sperm whale myoglobin.


===Crystal Structure of Human Myoglobin Mutant K45R===
X-ray crystal structure of a recombinant human myoglobin mutant at 2.8 A resolution.,Hubbard SR, Hendrickson WA, Lambright DG, Boxer SG J Mol Biol. 1990 May 20;213(2):215-8. PMID:2342104<ref>PMID:2342104</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 3rgk" style="background-color:#fffaf0;"></div>


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==See Also==
The line below this paragraph, {{ABSTRACT_PUBMED_2342104}}, adds the Publication Abstract to the page
*[[Myoglobin 3D structures|Myoglobin 3D structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 2342104 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_2342104}}
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</StructureSection>
==About this Structure==
[[3rgk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2mm1 2mm1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RGK OCA].
 
==Reference==
<ref group="xtra">PMID:2342104</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hubbard, S R.]]
[[Category: Large Structures]]
[[Category: Hubbard SR]]
Retrieved from "https://proteopedia.org/3rgk"