2a0s: Difference between revisions

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New page: left|200px<br /><applet load="2a0s" size="350" color="white" frame="true" align="right" spinBox="true" caption="2a0s, resolution 2.20Å" /> '''Crystal structure of...
 
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[[Image:2a0s.gif|left|200px]]<br /><applet load="2a0s" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2a0s, resolution 2.20&Aring;" />
'''Crystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution'''<br />


==About this Structure==
==Crystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution==
2A0S is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=BIO:'>BIO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/6-pyruvoyltetrahydropterin_synthase 6-pyruvoyltetrahydropterin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.12 4.2.3.12] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A0S OCA].  
<StructureSection load='2a0s' size='340' side='right'caption='[[2a0s]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
[[Category: 6-pyruvoyltetrahydropterin synthase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2a0s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A0S FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BIO:BIOPTERIN'>BIO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a0s OCA], [https://pdbe.org/2a0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a0s RCSB], [https://www.ebi.ac.uk/pdbsum/2a0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a0s ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A5K2B2_PLAVS A5K2B2_PLAVS]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a0/2a0s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a0s ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Plasmodium vivax]]
[[Category: Plasmodium vivax]]
[[Category: Protein complex]]
[[Category: Bosch J]]
[[Category: Bosch, J.]]
[[Category: Hol WGJ]]
[[Category: Hol, W.G.J.]]
[[Category: SGPP, Structural.Genomics.of.Pathogenic.Protozoa.Consortium.]]
[[Category: BIO]]
[[Category: ZN]]
[[Category: 6-pyruvoyl tetrahydropterin synthase]]
[[Category: plasmodium]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: ptps]]
[[Category: sgpp]]
[[Category: structural genomics]]
[[Category: structural genomics of pathogenic protozoa consortium]]
[[Category: vivax]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 17:52:04 2008''

Latest revision as of 07:17, 23 August 2023

Crystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution

2a0s, resolution 2.20Å

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