2a2t: Difference between revisions

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New page: left|200px<br /><applet load="2a2t" size="350" color="white" frame="true" align="right" spinBox="true" caption="2a2t, resolution 3.10Å" /> '''crystal structure of...
 
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[[Image:2a2t.gif|left|200px]]<br /><applet load="2a2t" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2a2t, resolution 3.10&Aring;" />
'''crystal structure of d(AAATATTT)'''<br />


==Overview==
==crystal structure of d(AAATATTT)==
The structure of the oligonucleotide duplex d(AAATATTT)(2) has been, obtained in two crystal forms. In both cases the duplexes show, Watson-Crick base pairs and are organized as a helical arrangement of, stacked oligonucleotides. The helices contain either 11 duplexes in seven, turns (form I) or 14 duplexes in nine turns (form II). As a result, the, crystals have rather large unit cells. Such an organization of DNA, duplexes has not been previously described in oligonucleotide crystal, structures. The columns of stacked duplexes are organized in a, pseudohexagonal arrangement. They do not show any direct lateral, interactions; instead, these are indirectly mediated by shared and, disordered hydrated ions. Such interactions are similar to those found in, DNA fibres. The structural parameters of the individual base steps, coincide with those found in other structures which contain CG terminal, base pairs.
<StructureSection load='2a2t' size='340' side='right'caption='[[2a2t]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[2a2t]] is a 11 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A2T FirstGlance]. <br>
2A2T is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=MN:'>MN</scene> and <scene name='pdbligand=CAC:'>CAC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2T OCA].
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a2t OCA], [https://pdbe.org/2a2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a2t RCSB], [https://www.ebi.ac.uk/pdbsum/2a2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a2t ProSAT]</span></td></tr>
Structure of a DNA duplex with all-AT base pairs., Valls N, Richter M, Subirana JA, Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1587-93. Epub 2005, Nov 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16301792 16301792]
</table>
[[Category: Protein complex]]
__TOC__
[[Category: Richter, M.]]
</StructureSection>
[[Category: Subirana, J.A.]]
[[Category: Large Structures]]
[[Category: Valls, N.]]
[[Category: Richter M]]
[[Category: CAC]]
[[Category: Subirana JA]]
[[Category: MN]]
[[Category: Valls N]]
[[Category: at]]
[[Category: cacodylate]]
[[Category: haso]]
[[Category: mn]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 17:53:09 2008''

Latest revision as of 13:40, 13 March 2024

crystal structure of d(AAATATTT)

2a2t, resolution 3.10Å

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