3pz2: Difference between revisions

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[[Image:3pz2.jpg|left|200px]]


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==Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 and lipid substrate GGPP==
The line below this paragraph, containing "STRUCTURE_3pz2", creates the "Structure Box" on the page.
<StructureSection load='3pz2' size='340' side='right'caption='[[3pz2]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3pz2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PZ2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PZ:(3R)-3-BENZYL-4-[(4-METHOXYPHENYL)SULFONYL]-1-[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPINE-7-CARBONITRILE'>3PZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GRG:GERANYLGERANYL+DIPHOSPHATE'>GRG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3pz2|  PDB=3pz2  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pz2 OCA], [https://pdbe.org/3pz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pz2 RCSB], [https://www.ebi.ac.uk/pdbsum/3pz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pz2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PGTA_RAT PGTA_RAT] Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.


===Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 and lipid substrate GGPP===
==See Also==
 
*[[Geranylgeranyl transferase 3D structures|Geranylgeranyl transferase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3pz2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PZ2 OCA].
[[Category: Large Structures]]
 
[[Category: Rattus norvegicus]]
==Reference==
[[Category: Alexandrov K]]
<ref group="xtra">PMID:021520375</ref><references group="xtra"/>
[[Category: Blankenfeldt W]]
[[Category: Mus musculus]]
[[Category: Bon RS]]
[[Category: Protein geranylgeranyltransferase type II]]
[[Category: Goody RS]]
[[Category: Alexandrov, K.]]
[[Category: Guo Z]]
[[Category: Blankenfeldt, W.]]
[[Category: Stigter EA]]
[[Category: Bon, R S.]]
[[Category: Waldmann H]]
[[Category: Goody, R S.]]
[[Category: Guo, Z.]]
[[Category: Stigter, E A.]]
[[Category: Waldmann, H.]]
Retrieved from "https://proteopedia.org/3pz2"