2l5f: Difference between revisions

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[[Image:2l5f.jpg|left|200px]]


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==Solution structure of the tandem WW domains from HYPA/FBP11==
The line below this paragraph, containing "STRUCTURE_2l5f", creates the "Structure Box" on the page.
<StructureSection load='2l5f' size='340' side='right'caption='[[2l5f]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2l5f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L5F FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l5f OCA], [https://pdbe.org/2l5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l5f RCSB], [https://www.ebi.ac.uk/pdbsum/2l5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l5f ProSAT]</span></td></tr>
{{STRUCTURE_2l5f|  PDB=2l5f  |  SCENE=  }}
</table>
 
== Function ==
===Solution structure of the tandem WW domains from HYPA/FBP11===
[https://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref>
 
== References ==
 
<references/>
==About this Structure==
__TOC__
[[2l5f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L5F OCA].  
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hu, H.]]
[[Category: Large Structures]]
[[Category: Jiang, Y.]]
[[Category: Hu H]]
[[Category: Jiang Y]]