2cnv: Difference between revisions

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New page: left|200px<br /> <applet load="2cnv" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cnv, resolution 2.00Å" /> '''SAICAR-SYNTHASE FRO...
 
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[[Image:2cnv.gif|left|200px]]<br />
<applet load="2cnv" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2cnv, resolution 2.00&Aring;" />
'''SAICAR-SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED SAICAR'''<br />


==About this Structure==
==SAICAR-synthase from Saccharomyces cerevisiae complexed SAICAR==
2CNV is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]] with SO4, ACE, ASP and SSS as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.6 6.3.2.6]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CNV OCA]].
<StructureSection load='2cnv' size='340' side='right'caption='[[2cnv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2cnv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CNV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SSS:N-{[5-AMINO-1-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-1H-IMIDAZOL-4-YL]CARBONYL}-L-ASPARTIC+ACID'>SSS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cnv OCA], [https://pdbe.org/2cnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cnv RCSB], [https://www.ebi.ac.uk/pdbsum/2cnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cnv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PUR7_YEAST PUR7_YEAST]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/2cnv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cnv ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[SAICAR synthetase|SAICAR synthetase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Antonyuk SV]]
[[Category: Antonyuk, S.V.]]
[[Category: Barynin VV]]
[[Category: Barynin, V.V.]]
[[Category: Grebenko AI]]
[[Category: Grebenko, A.I.]]
[[Category: Lamzin VS]]
[[Category: Lamzin, V.S.]]
[[Category: Levdikov VM]]
[[Category: Levdikov, V.M.]]
[[Category: Melik-Adamyan VR]]
[[Category: Melik-Adamyan, W.R.]]
[[Category: Popov AN]]
[[Category: Popov, A.N.]]
[[Category: Urusova DV]]
[[Category: Urusova, D.V.]]
[[Category: ACE]]
[[Category: ASP]]
[[Category: SO4]]
[[Category: SSS]]
[[Category: acetylation]]
[[Category: atpbinding protein]]
[[Category: phosphoribosylaminoimidazolesuccinocarboxamide (saicar) syn ligase]]
[[Category: purine biosynthesis]]
[[Category: synthetase]]
 
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Retrieved from "https://proteopedia.org/2cnv"