2lcs: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 2lcs is ~~ON HOLD~~

==Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p==

~~Authors~~: ~~Gorelik~~, M., ~~Davidson~~, A.R.

== Structural highlights ==

<table><tr><td colspan='2'>[[2lcs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LCS FirstGlance]. <br>

~~Description~~: ~~Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p~~

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lcs OCA], [https://pdbe.org/2lcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lcs RCSB], [https://www.ebi.ac.uk/pdbsum/2lcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lcs ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/NBP2_YEAST NBP2_YEAST] Negatively regulates the high-osmolarity glycerol (HOG) pathway through its negative regulation of the HOG1 kinase activity. Mediates the binding between the PTC1 phosphatase and the PBS2 MAP/ERK kinase (MEK). With PTC1, regulates endoplasmic reticulum inheritance through the cell wall integrity (CWI) MAPK pathway by modulating the MAPK, SLT2.<ref>PMID:14573466</ref> <ref>PMID:14685261</ref> <ref>PMID:16977319</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Saccharomyces cerevisiae S288C]]

[[Category: Davidson AR]]

[[Category: Gorelik M]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 2lcs is ON HOLD
+==Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p==
+<StructureSection load='2lcs' size='340' side='right'caption='[[2lcs]]' scene=''>
-Authors: Gorelik, M., Davidson, A.R.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2lcs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LCS FirstGlance]. <br>
-Description: Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lcs OCA], [https://pdbe.org/2lcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lcs RCSB], [https://www.ebi.ac.uk/pdbsum/2lcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lcs ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NBP2_YEAST NBP2_YEAST] Negatively regulates the high-osmolarity glycerol (HOG) pathway through its negative regulation of the HOG1 kinase activity. Mediates the binding between the PTC1 phosphatase and the PBS2 MAP/ERK kinase (MEK). With PTC1, regulates endoplasmic reticulum inheritance through the cell wall integrity (CWI) MAPK pathway by modulating the MAPK, SLT2.<ref>PMID:14573466</ref> <ref>PMID:14685261</ref> <ref>PMID:16977319</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Saccharomyces cerevisiae S288C]]
+[[Category: Davidson AR]]
+[[Category: Gorelik M]]