3s3p: Difference between revisions
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New page: '''Unreleased structure''' The entry 3s3p is ON HOLD Authors: Lindemann, I., Heine, A., Klebe, G. Description: Transglutaminase 2 in complex with a novel inhibitor |
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==Transglutaminase 2 in complex with a novel inhibitor== | |||
<StructureSection load='3s3p' size='340' side='right'caption='[[3s3p]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3s3p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S3P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S3P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XW1:(2S)-2-AMINO-7-ETHOXY-7-OXOHEPTANOIC+ACID'>XW1</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s3p OCA], [https://pdbe.org/3s3p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s3p RCSB], [https://www.ebi.ac.uk/pdbsum/3s3p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s3p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TGM2_HUMAN TGM2_HUMAN] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Heine A]] | |||
[[Category: Klebe G]] | |||
[[Category: Lindemann I]] | |||
Latest revision as of 08:14, 6 December 2023
Transglutaminase 2 in complex with a novel inhibitor
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