2cb1: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
New page: left|200px<br /><applet load="2cb1" size="350" color="white" frame="true" align="right" spinBox="true" caption="2cb1, resolution 2.00Å" /> '''CRYSTAL STRUCTURE OF...
 
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(16 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2cb1.jpg|left|200px]]<br /><applet load="2cb1" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2cb1, resolution 2.00&Aring;" />
'''CRYSTAL STRUCTURE OF O-ACTETYL HOMOSERINE SULFHYDRYLASE FROM THERMUS THERMOPHILUS HB8,OAH2.'''<br />


==About this Structure==
==Crystal Structure of O-actetyl Homoserine Sulfhydrylase From Thermus Thermophilus HB8,OAH2.==
2CB1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Active as [http://en.wikipedia.org/wiki/O-acetylhomoserine_aminocarboxypropyltransferase O-acetylhomoserine aminocarboxypropyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.49 2.5.1.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CB1 OCA].  
<StructureSection load='2cb1' size='340' side='right'caption='[[2cb1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: O-acetylhomoserine aminocarboxypropyltransferase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2cb1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CB1 FirstGlance]. <br>
[[Category: Thermus thermophilus]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Agari, Y.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
[[Category: Ebihara, A.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cb1 OCA], [https://pdbe.org/2cb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cb1 RCSB], [https://www.ebi.ac.uk/pdbsum/2cb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cb1 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cb1 TOPSAN]</span></td></tr>
[[Category: Imagawa, T.]]
</table>
[[Category: Kanagawa, M.]]
== Function ==
[[Category: Kuramitsu, S.]]
[https://www.uniprot.org/uniprot/METY2_THET8 METY2_THET8] Catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway. Has weak activity with O-acetyl-L-serine, O-phospho-L-serine, L-serine, O-succinyl-L-homoserine and L-homoserine. Shows a very low CTT gamma-synthase activity.<ref>PMID:15215603</ref>
[[Category: Kuroishi, C.]]
== Evolutionary Conservation ==
[[Category: Nakagawa, N.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
Check<jmol>
[[Category: Tsuge, H.]]
  <jmolCheckbox>
[[Category: Utsunomiya, H.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cb/2cb1_consurf.spt"</scriptWhenChecked>
[[Category: Yokoyama, S.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: homoserine]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: lyase]]
  </jmolCheckbox>
[[Category: plp enzyme]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cb1 ConSurf].
[[Category: riken structural genomics/proteomics initiative]]
<div style="clear:both"></div>
[[Category: rsgi]]
== References ==
[[Category: structural genomics]]
<references/>
[[Category: sulfhydrylase]]
__TOC__
 
</StructureSection>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 18:39:46 2008''
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB8]]
[[Category: Agari Y]]
[[Category: Ebihara A]]
[[Category: Imagawa T]]
[[Category: Kanagawa M]]
[[Category: Kuramitsu S]]
[[Category: Kuroishi C]]
[[Category: Nakagawa N]]
[[Category: Tsuge H]]
[[Category: Utsunomiya H]]
[[Category: Yokoyama S]]
Retrieved from "https://proteopedia.org/2cb1"