3s0i: Difference between revisions

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'''Unreleased structure'''


The entry 3s0i is ON HOLD  until Paper Publication
==Crystal Structure of D48V mutant of Human Glycolipid Transfer Protein complexed with 3-O-sulfo galactosylceramide containing nervonoyl acyl chain==
 
<StructureSection load='3s0i' size='340' side='right'caption='[[3s0i]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
Authors: Samygina, V., Cabo-Bilbao, A., Popov, A.N., Ochoa-Lizarralde, B., Patel, D.J., Brown, R.E., Malinina, L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3s0i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S0I FirstGlance]. <br>
Description: Crystal Structure of D48V mutant of Human Glycolipid Transfer Protein complexed with 3-O-sulfo galactosylceramide containing nervonoyl acid chains
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIS:(15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE'>CIS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s0i OCA], [https://pdbe.org/3s0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s0i RCSB], [https://www.ebi.ac.uk/pdbsum/3s0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s0i ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Brown RE]]
[[Category: Cabo-Bilbao A]]
[[Category: Malinina L]]
[[Category: Ochoa-Lizarralde B]]
[[Category: Patel DJ]]
[[Category: Popov AN]]
[[Category: Samygina V]]

Latest revision as of 12:42, 14 March 2024

Crystal Structure of D48V mutant of Human Glycolipid Transfer Protein complexed with 3-O-sulfo galactosylceramide containing nervonoyl acyl chain

3s0i, resolution 1.50Å

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