2l4t: Difference between revisions

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[[Image:2l4t.png|left|200px]]


<!--
==GIP/Glutaminase L peptide complex==
The line below this paragraph, containing "STRUCTURE_2l4t", creates the "Structure Box" on the page.
<StructureSection load='2l4t' size='340' side='right'caption='[[2l4t]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2l4t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L4T FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l4t OCA], [https://pdbe.org/2l4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l4t RCSB], [https://www.ebi.ac.uk/pdbsum/2l4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l4t ProSAT]</span></td></tr>
{{STRUCTURE_2l4t|  PDB=2l4t  |  SCENE=  }}
</table>
 
== Function ==
===GIP/Glutaminase L peptide complex===
[https://www.uniprot.org/uniprot/TX1B3_HUMAN TX1B3_HUMAN] May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.<ref>PMID:10940294</ref> <ref>PMID:16855024</ref> <ref>PMID:21139582</ref>  
 
== References ==
 
<references/>
<!--
__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_21417405}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 21417405 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_21417405}}
 
==About this Structure==
[[2l4t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L4T OCA].  
 
==Reference==
<ref group="xtra">PMID:021417405</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Banerjee, M.]]
[[Category: Large Structures]]
[[Category: Bhaskaran, R.]]
[[Category: Banerjee M]]
[[Category: Mohanty, S.]]
[[Category: Bhaskaran R]]
[[Category: Ovee, M.]]
[[Category: Mohanty S]]
[[Category: Zoetewey, D L.]]
[[Category: Ovee M]]
[[Category: Gip]]
[[Category: Zoetewey DL]]
[[Category: Glutaminase l]]
[[Category: Pdz domain]]
[[Category: Protein binding]]
Retrieved from "https://proteopedia.org/2l4t"