2yj0: Difference between revisions
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==X-ray structure of chemically engineered Mycobacterium tuberculosis Dodecin== | |||
<StructureSection load='2yj0' size='340' side='right'caption='[[2yj0]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2yj0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YJ0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=420:N-[2-({[5-(DIMETHYLAMINO)NAPHTHALEN-1-YL]SULFONYL}AMINO)ETHYL]-2-IODOACETAMIDE'>420</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yj0 OCA], [https://pdbe.org/2yj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yj0 RCSB], [https://www.ebi.ac.uk/pdbsum/2yj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yj0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q8VK10_MYCTO Q8VK10_MYCTO] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The suitability for chemical engineering of the highly symmetrical Mycobacterium tuberculosis dodecin was investigated, its inner cavity providing a large compartment shields introduced compounds from bulk solvent. Hybrids were obtained by S-alkylation of cysteine mutants and characterized by spectroscopic methods, including the crystal structures of wild type and biohybrid dodecins. | |||
Chemical engineering of Mycobacterium tuberculosis dodecin hybrids.,Vinzenz X, Grosse W, Linne U, Meissner B, Essen LO Chem Commun (Camb). 2011 Oct 21;47(39):11071-3. Epub 2011 Sep 6. PMID:21897938<ref>PMID:21897938</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 2yj0" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Essen L-O]] | |||
[[Category: Grosse W]] | |||
[[Category: Linne U]] | |||
[[Category: Meissner B]] | |||
[[Category: Vinzenz X]] | |||
Latest revision as of 10:53, 20 December 2023
X-ray structure of chemically engineered Mycobacterium tuberculosis Dodecin
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