2f7f: Difference between revisions

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New page: left|200px<br /><applet load="2f7f" size="350" color="white" frame="true" align="right" spinBox="true" caption="2f7f, resolution 2.00Å" /> '''Crystal structure of...
 
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[[Image:2f7f.gif|left|200px]]<br /><applet load="2f7f" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2f7f, resolution 2.00&Aring;" />
'''Crystal structure of Enterococcus faecalis putative nicotinate phosphoribosyltransferase, NEW YORK STRUCTURAL GENOMICS CONSORTIUM'''<br />


==About this Structure==
==Crystal structure of Enterococcus faecalis putative nicotinate phosphoribosyltransferase, NEW YORK STRUCTURAL GENOMICS CONSORTIUM==
2F7F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis_v583 Enterococcus faecalis v583] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=NIO:'>NIO</scene>, <scene name='pdbligand=DPO:'>DPO</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Nicotinate_phosphoribosyltransferase Nicotinate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.11 2.4.2.11] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F7F OCA].
<StructureSection load='2f7f' size='340' side='right'caption='[[2f7f]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Enterococcus faecalis v583]]
== Structural highlights ==
[[Category: Nicotinate phosphoribosyltransferase]]
<table><tr><td colspan='2'>[[2f7f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F7F FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Almo, S.C.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NIO:NICOTINIC+ACID'>NIO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Burley, S.K.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f7f OCA], [https://pdbe.org/2f7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f7f RCSB], [https://www.ebi.ac.uk/pdbsum/2f7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f7f ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2f7f TOPSAN]</span></td></tr>
[[Category: NYSGXRC, New.York.Structural.GenomiX.Research.Consortium.]]
</table>
[[Category: Patskovsky, Y.]]
== Function ==
[[Category: DPO]]
[https://www.uniprot.org/uniprot/Q830Y8_ENTFA Q830Y8_ENTFA] Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP (By similarity).[SAAS:SAAS007229_004_012126]
[[Category: GOL]]
== Evolutionary Conservation ==
[[Category: NIO]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: SO4]]
Check<jmol>
[[Category: new york structural genomix research consortium]]
  <jmolCheckbox>
[[Category: nysgxrc]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/2f7f_consurf.spt"</scriptWhenChecked>
[[Category: protein structure initiative]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: psi]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: structural genomics]]
  </jmolCheckbox>
[[Category: transferase]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f7f ConSurf].
 
<div style="clear:both"></div>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 19:29:17 2008''
__TOC__
</StructureSection>
[[Category: Enterococcus faecalis V583]]
[[Category: Large Structures]]
[[Category: Almo SC]]
[[Category: Burley SK]]
[[Category: Patskovsky Y]]