3p45: Difference between revisions

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[[Image:3p45.jpg|left|200px]]


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==Crystal structure of apo-caspase-6 at physiological pH==
The line below this paragraph, containing "STRUCTURE_3p45", creates the "Structure Box" on the page.
<StructureSection load='3p45' size='340' side='right'caption='[[3p45]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3p45]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P45 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p45 OCA], [https://pdbe.org/3p45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p45 RCSB], [https://www.ebi.ac.uk/pdbsum/3p45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p45 ProSAT]</span></td></tr>
{{STRUCTURE_3p45|  PDB=3p45  |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.


===Crystal structure of apo-caspase-6 at physiological pH===
==See Also==
 
*[[Caspase 3D structures|Caspase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3p45]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P45 OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Dominguez, C.]]
[[Category: Large Structures]]
[[Category: Kiselyov, A.]]
[[Category: Dominguez C]]
[[Category: Lamers, M B.A C.]]
[[Category: Kiselyov A]]
[[Category: Maillard, M.]]
[[Category: Lamers MBAC]]
[[Category: Mueller, I.]]
[[Category: Maillard M]]
[[Category: Munoz, I.]]
[[Category: Mueller I]]
[[Category: Ritchie, A J.]]
[[Category: Munoz I]]
[[Category: Competitive inhibition]]
[[Category: Ritchie AJ]]
[[Category: Huntington's disease]]
[[Category: Hydrolase]]
[[Category: Mature apo-caspase-6]]
[[Category: Physiological ph]]
[[Category: Protease]]
Retrieved from "https://proteopedia.org/3p45"