3rbv: Difference between revisions

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[[Image:3rbv.jpg|left|200px]]


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==Crystal Structure of KijD10, a 3-ketoreductase from Actinomadura kijaniata incomplex with NADP==
The line below this paragraph, containing "STRUCTURE_3rbv", creates the "Structure Box" on the page.
<StructureSection load='3rbv' size='340' side='right'caption='[[3rbv]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3rbv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomadura_kijaniata Actinomadura kijaniata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RBV FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_3rbv|  PDB=3rbv  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rbv OCA], [https://pdbe.org/3rbv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rbv RCSB], [https://www.ebi.ac.uk/pdbsum/3rbv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rbv ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of KijD10, a 3-ketoreductase from Actinomadura kijaniata incomplex with NADP===
== Function ==
 
[https://www.uniprot.org/uniprot/KIJDR_ACTKI KIJDR_ACTKI] Involved in the biosynthesis of L-digitoxose, an unusual dideoxysugar attached to various pharmacologically active natural products, including the antitumor antibiotic tetrocarcin A, and the antibiotics kijanimicin and jadomycin B. Catalyzes the reduction of the C-3 keto moiety of dTDP-3,4-diketo-2,6-dideoxy-alpha-D-glucose to yield dTDP-4-keto-2,6-dideoxy-alpha-D-glucose. Also able to reduce dTDP-3-keto-6-deoxy-D-galactose and dTDP-3-keto-6-deoxy-D-glucose to yield dTDP-fucose and dTDP-quinovose, respectively.<ref>PMID:21598943</ref>  
 
== References ==
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<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_21598943}}, adds the Publication Abstract to the page
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</StructureSection>
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{{ABSTRACT_PUBMED_21598943}}
 
==About this Structure==
[[3rbv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinomadura_kijaniata Actinomadura kijaniata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBV OCA].  
 
==Reference==
<ref group="xtra">PMID:021598943</ref><references group="xtra"/>
[[Category: Actinomadura kijaniata]]
[[Category: Actinomadura kijaniata]]
[[Category: Holden, H M.]]
[[Category: Large Structures]]
[[Category: Kubiak, R L.]]
[[Category: Holden HM]]
[[Category: Ketoreductase]]
[[Category: Kubiak RL]]
[[Category: Nadp binding]]
[[Category: Sugar binding protein]]
[[Category: Sugar biosynthesis]]

Latest revision as of 10:53, 21 February 2024

Crystal Structure of KijD10, a 3-ketoreductase from Actinomadura kijaniata incomplex with NADP

3rbv, resolution 1.90Å

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