3siu: Difference between revisions
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New page: '''Unreleased structure''' The entry 3siu is ON HOLD Authors: Liu, S., Ghalei, H., Luhrmann, R., Wahl, M.C. Description: Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, monome... |
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==Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, monomeric form== | |||
<StructureSection load='3siu' size='340' side='right'caption='[[3siu]], [[Resolution|resolution]] 2.63Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3siu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SIU FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.626Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3siu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3siu OCA], [https://pdbe.org/3siu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3siu RCSB], [https://www.ebi.ac.uk/pdbsum/3siu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3siu ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NH2L1_HUMAN NH2L1_HUMAN] Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.<ref>PMID:10545122</ref> <ref>PMID:17412961</ref> | |||
==See Also== | |||
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | |||
*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ghalei H]] | |||
[[Category: Liu S]] | |||
[[Category: Luhrmann R]] | |||
[[Category: Wahl MC]] | |||
Latest revision as of 12:58, 14 March 2024
Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, monomeric form
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