3sfk: Difference between revisions

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[[Image:3sfk.jpg|left|200px]]


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==Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM267==
The line below this paragraph, containing "STRUCTURE_3sfk", creates the "Structure Box" on the page.
<StructureSection load='3sfk' size='340' side='right'caption='[[3sfk]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3sfk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SFK FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D67:2-(1,1-DIFLUOROETHYL)-5-METHYL-N-[4-(TRIFLUOROMETHYL)PHENYL][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE'>D67</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene></td></tr>
{{STRUCTURE_3sfk|  PDB=3sfk  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sfk OCA], [https://pdbe.org/3sfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sfk RCSB], [https://www.ebi.ac.uk/pdbsum/3sfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sfk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYRD_PLAF7 PYRD_PLAF7] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.


===Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM267===
==See Also==
 
*[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_21696174}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 21696174 is the PubMed ID number.
[[Category: Plasmodium falciparum 3D7]]
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[[Category: Deng X]]
{{ABSTRACT_PUBMED_21696174}}
[[Category: Phillips M]]
 
==About this Structure==
[[3sfk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFK OCA].
 
==Reference==
<ref group="xtra">PMID:021696174</ref><references group="xtra"/>
[[Category: Dihydroorotate dehydrogenase]]
[[Category: Plasmodium falciparum 3d7]]
[[Category: Deng, X.]]
[[Category: Phillips, M.]]
[[Category: Alpha beta barrel oxidoreductase]]
[[Category: Alpha beta fold]]
[[Category: Flavoprotein]]
[[Category: Fmn]]
[[Category: Inhibitor dsm267]]
[[Category: Mitochondrion inner membrane]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Plasmodium falciparum membrane mitochondrion]]
[[Category: Pyrimidine biosynthesis]]
Retrieved from "https://proteopedia.org/3sfk"