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'''Unreleased structure'''


The entry 3srk is ON HOLD
==A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase==
<StructureSection load='3srk' size='340' side='right'caption='[[3srk]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3srk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SRK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LSA:1,2-BENZISOTHIAZOL-3(2H)-ONE+1,1-DIOXIDE'>LSA</scene>, <scene name='pdbligand=PTK:PYRENE-1,3,6,8-TETRASULFONIC+ACID'>PTK</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3srk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3srk OCA], [https://pdbe.org/3srk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3srk RCSB], [https://www.ebi.ac.uk/pdbsum/3srk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3srk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KPYK_LEIME KPYK_LEIME]


Authors: Morgan, H.P., Walsh, M., Blackburn, E.A., Wear, M.A., Boxer, M., Shen, M., McNae, I.W., Michels, P.A.M., Auld, D.S., Fothergill-Gilmore, L.A., Walkinshaw, M.D.
==See Also==
 
*[[Pyruvate kinase 3D structures|Pyruvate kinase 3D structures]]
Description: A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Leishmania mexicana]]
[[Category: Auld DS]]
[[Category: Blackburn EA]]
[[Category: Boxer M]]
[[Category: Fothergill-Gilmore LA]]
[[Category: McNae IW]]
[[Category: Michels PAM]]
[[Category: Morgan HP]]
[[Category: Shen M]]
[[Category: Walkinshaw MD]]
[[Category: Walsh M]]
[[Category: Wear MA]]
Retrieved from "https://proteopedia.org/3srk"