1vte: Difference between revisions
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< | ==MOLECULAR STRUCTURE OF NICKED DNA. MODEL A4== | ||
The | <StructureSection load='1vte' size='340' side='right'caption='[[1vte]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1vte]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VTE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vte OCA], [https://pdbe.org/1vte PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vte RCSB], [https://www.ebi.ac.uk/pdbsum/1vte PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vte ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The molecular structure of a nicked dodecamer DNA double helix, made of a ternary system containing d(CGCGAAAACGCG) + d(CGCGTT) + d(TTCGCG) oligonucleotides, has been determined by x-ray diffraction analysis at 3 A resolution. The molecule adopts a B-DNA conformation, not unlike those found in intact dodecamer DNA molecules crystallized in a somewhat different crystal lattice, despite a gap due to the absence of a phosphate group in the molecule. The helix has a distinct narrow minor groove near the center of the molecule at the AAAA region. This suggests that the internal stabilizing forces due to base stacking and hydrogen-bonding interactions are sufficient to overcome the loss of connectivity associated with the disruption of the covalent backbone of DNA. | |||
Molecular structure of nicked DNA: a substrate for DNA repair enzymes.,Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A Proc Natl Acad Sci U S A. 1990 Apr;87(7):2526-30. PMID:2320572<ref>PMID:2320572</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
== | </div> | ||
<div class="pdbe-citations 1vte" style="background-color:#fffaf0;"></div> | |||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Rich | [[Category: Large Structures]] | ||
[[Category: | [[Category: Synthetic construct]] | ||
[[Category: | [[Category: Aymani J]] | ||
[[Category: | [[Category: Coll M]] | ||
[[Category: Rich A]] | |||
[[Category: Van Boom JH]] | |||
[[Category: Van Der Marel GA]] | |||
[[Category: Wang AH-J]] | |||
Latest revision as of 00:05, 28 December 2023
MOLECULAR STRUCTURE OF NICKED DNA. MODEL A4
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