3qvz: Difference between revisions

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~~[[Image:3qvz.png|left|200px]]~~

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==Crystal structure of the Zn-RIDC1 complex stabilized by BMOE crosslinks cocrystallized in the presence of Cu(II)==

~~The line below this paragraph, containing~~ "~~STRUCTURE_3qvz~~"~~, creates the~~ "~~Structure Box~~" ~~on the page~~.

~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)

== Structural highlights ==

~~or the SCENE parameter~~ (~~which sets the initial~~ scene ~~displayed when the page is loaded)~~,

<table><tr><td colspan='2'>[[3qvz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QVZ FirstGlance]. <br>

~~or leave the SCENE parameter empty for the default display~~.

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.64Å</td></tr>

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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=ME7:1,1-ETHANE-1,2-DIYLBIS(1H-PYRROLE-2,5-DIONE)'>ME7</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

~~{{STRUCTURE_3qvz| PDB~~=~~3qvz | SCENE~~= }}

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qvz OCA], [https://pdbe.org/3qvz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qvz RCSB], [https://www.ebi.ac.uk/pdbsum/3qvz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qvz ProSAT]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

Here, we report that the approach of metal-templated ligand synthesis can be applied to construct a dimeric protein assembly ((BMOE)RIDC1(2)), which is stabilized by noncovalent interactions and flexible covalent cross-linkers around the Zn templates. Despite its flexibility, (BMOE)RIDC1(2) selectively binds Zn(II) over other divalent metals and undergoes dimerization upon metal binding. Such simultaneous fulfillment of plasticity and selectivity is a hallmark of cellular signaling events that involve ligand/metal-induced protein dimerization.

~~===Crystal structure~~ of ~~the~~ Zn-~~RIDC1 complex stabilized by BMOE crosslinks cocrystallized in the presence of Cu(II)===~~

Templated Construction of a Zn-Selective Protein Dimerization Motif.,Salgado EN, Brodin JD, To MM, Tezcan FA Inorg Chem. 2011 Jun 7. PMID:21648390<ref>PMID:21648390</ref>

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~<!--~~

==See Also==

~~The line below this paragraph, {{ABSTRACT_PUBMED_21648390}}, adds the Publication Abstract to the page~~

*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]

~~(as it appears on PubMed at http://www.pubmed.gov), where 21648390 is the PubMed ID number.~~

== References ==

~~-->~~

~~{{ABSTRACT_PUBMED_21648390}}~~

__TOC__

</StructureSection>

==~~About this Structure~~==

[[~~3qvz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli~~]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVZ OCA~~].

==~~Reference~~==

<~~ref group="xtra">PMID:021648390<~~/~~ref~~><~~references group="xtra"~~/>

[[Category: Escherichia coli]]

[[Category: ~~Salgado, E N.~~]]

[[Category: Large Structures]]

[[Category: ~~Tezcan, F A.~~]]

[[Category: Salgado EN]]

[[Category: ~~Four-helix bundle]]~~

[[Category: Tezcan FA]]

~~[[Category: Oxidoreductase~~]]

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@@ Line 1: / Line 1: @@
-[[Image:3qvz.png|left|200px]]
-<!--
+==Crystal structure of the Zn-RIDC1 complex stabilized by BMOE crosslinks cocrystallized in the presence of Cu(II)==
-The line below this paragraph, containing "STRUCTURE_3qvz", creates the "Structure Box" on the page.
+<StructureSection load='3qvz' size='340' side='right'caption='[[3qvz]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3qvz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QVZ FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.64&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=ME7:1,1-ETHANE-1,2-DIYLBIS(1H-PYRROLE-2,5-DIONE)'>ME7</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_3qvz|  PDB=3qvz  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qvz OCA], [https://pdbe.org/3qvz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qvz RCSB], [https://www.ebi.ac.uk/pdbsum/3qvz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qvz ProSAT]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Here, we report that the approach of metal-templated ligand synthesis can be applied to construct a dimeric protein assembly ((BMOE)RIDC1(2)), which is stabilized by noncovalent interactions and flexible covalent cross-linkers around the Zn templates. Despite its flexibility, (BMOE)RIDC1(2) selectively binds Zn(II) over other divalent metals and undergoes dimerization upon metal binding. Such simultaneous fulfillment of plasticity and selectivity is a hallmark of cellular signaling events that involve ligand/metal-induced protein dimerization.
-===Crystal structure of the Zn-RIDC1 complex stabilized by BMOE crosslinks cocrystallized in the presence of Cu(II)===
+Templated Construction of a Zn-Selective Protein Dimerization Motif.,Salgado EN, Brodin JD, To MM, Tezcan FA Inorg Chem. 2011 Jun 7. PMID:21648390<ref>PMID:21648390</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 3qvz" style="background-color:#fffaf0;"></div>
-<!--
+==See Also==
-The line below this paragraph, {{ABSTRACT_PUBMED_21648390}}, adds the Publication Abstract to the page
+*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 21648390 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_21648390}}
+__TOC__
+</StructureSection>
-==About this Structure==
-[[3qvz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVZ OCA].
-==Reference==
-<ref group="xtra">PMID:021648390</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Salgado, E N.]]
+[[Category: Large Structures]]
-[[Category: Tezcan, F A.]]
+[[Category: Salgado EN]]
-[[Category: Four-helix bundle]]
+[[Category: Tezcan FA]]
-[[Category: Oxidoreductase]]