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New page: left|200px<br /><applet load="2htt" size="350" color="white" frame="true" align="right" spinBox="true" caption="2htt, resolution 2.60Å" /> '''Ruthenium Hexammine ...
 
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[[Image:2htt.gif|left|200px]]<br /><applet load="2htt" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2htt, resolution 2.60&Aring;" />
'''Ruthenium Hexammine ion interactions with Z-DNA'''<br />


==About this Structure==
==Ruthenium Hexammine ion interactions with Z-DNA==
2HTT is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=NRU:'>NRU</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA].
<StructureSection load='2htt' size='340' side='right'caption='[[2htt]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
[[Category: Protein complex]]
== Structural highlights ==
[[Category: Bharanidharan, D.]]
<table><tr><td colspan='2'>[[2htt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HTT FirstGlance]. <br>
[[Category: Gautham, N.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
[[Category: Thiyagarajan, S.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NRU:RUTHENIUM+(III)+HEXAAMINE+ION'>NRU</scene></td></tr>
[[Category: NRU]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2htt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2htt OCA], [https://pdbe.org/2htt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2htt RCSB], [https://www.ebi.ac.uk/pdbsum/2htt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2htt ProSAT]</span></td></tr>
[[Category: double helix]]
</table>
[[Category: z-dna]]
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity.


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 20:28:35 2008''
Hexammineruthenium(III) ion interactions with Z-DNA.,Bharanidharan D, Thiyagarajan S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080<ref>PMID:18084080</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2htt" style="background-color:#fffaf0;"></div>
 
==See Also==
*[[Z-DNA|Z-DNA]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Bharanidharan D]]
[[Category: Gautham N]]
[[Category: Thiyagarajan S]]
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