2if2: Difference between revisions

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New page: left|200px<br /><applet load="2if2" size="350" color="white" frame="true" align="right" spinBox="true" caption="2if2, resolution 3.00Å" /> '''Crystal Structure of...
 
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[[Image:2if2.gif|left|200px]]<br /><applet load="2if2" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2if2, resolution 3.00&Aring;" />
'''Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.'''<br />


==About this Structure==
==Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72.==
2IF2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dephospho-CoA_kinase Dephospho-CoA kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.24 2.7.1.24] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF2 OCA].  
<StructureSection load='2if2' size='340' side='right'caption='[[2if2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
[[Category: Aquifex aeolicus]]
== Structural highlights ==
[[Category: Dephospho-CoA kinase]]
<table><tr><td colspan='2'>[[2if2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IF2 FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
[[Category: Acton, T.B.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Baran, M.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2if2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2if2 OCA], [https://pdbe.org/2if2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2if2 RCSB], [https://www.ebi.ac.uk/pdbsum/2if2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2if2 ProSAT], [https://www.topsan.org/Proteins/NESGC/2if2 TOPSAN]</span></td></tr>
[[Category: Cunningham, K.]]
</table>
[[Category: Fang, Y.]]
== Function ==
[[Category: Forouhar, F.]]
[https://www.uniprot.org/uniprot/COAE_AQUAE COAE_AQUAE] Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity).
[[Category: Hunt, J.F.]]
== Evolutionary Conservation ==
[[Category: Hussain, A.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Hussain, M.]]
Check<jmol>
[[Category: Liu, J.]]
  <jmolCheckbox>
[[Category: Ma, L.C.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/if/2if2_consurf.spt"</scriptWhenChecked>
[[Category: Montelione, G.T.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: NESG, Northeast.Structural.Genomics.Consortium.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Rost, B.]]
  </jmolCheckbox>
[[Category: Seetharaman, J.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2if2 ConSurf].
[[Category: Tong, L.]]
<div style="clear:both"></div>
[[Category: Wu, M.]]
__TOC__
[[Category: Xiao, R.]]
</StructureSection>
[[Category: EDO]]
[[Category: Aquifex aeolicus VF5]]
[[Category: SO4]]
[[Category: Large Structures]]
[[Category: alpha-beta protein]]
[[Category: Acton TB]]
[[Category: nesg]]
[[Category: Baran M]]
[[Category: northeast structural genomics consortium]]
[[Category: Cunningham K]]
[[Category: protein structure initiative]]
[[Category: Fang Y]]
[[Category: psi-2]]
[[Category: Forouhar F]]
[[Category: structural genomics]]
[[Category: Hunt JF]]
 
[[Category: Hussain A]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 20:39:55 2008''
[[Category: Hussain M]]
[[Category: Liu J]]
[[Category: Ma LC]]
[[Category: Montelione GT]]
[[Category: Rost B]]
[[Category: Seetharaman J]]
[[Category: Tong L]]
[[Category: Wu M]]
[[Category: Xiao R]]