3s61: Difference between revisions

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[[Image:3s61.png|left|200px]]


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==Reduced Form of Ornithine Hydroxylase (PvdA) from Pseudomonas aeruginosa==
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<StructureSection load='3s61' size='340' side='right'caption='[[3s61]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3s61]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S61 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S61 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.03&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene></td></tr>
{{STRUCTURE_3s61|  PDB=3s61  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s61 OCA], [https://pdbe.org/3s61 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s61 RCSB], [https://www.ebi.ac.uk/pdbsum/3s61 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s61 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PVDA_PSEAE PVDA_PSEAE] Catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr-L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate.<ref>PMID:17015659</ref> <ref>PMID:19368334</ref> <ref>PMID:8106324</ref>  


===Reduced Form of Ornithine Hydroxylase (PvdA) from Pseudomonas aeruginosa===
==See Also==
 
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
 
== References ==
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_21757711}}
 
==About this Structure==
[[3s61]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S61 OCA].
 
==Reference==
<ref group="xtra">PMID:021757711</ref><references group="xtra"/>
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Lamb, A L.]]
[[Category: Lamb AL]]
[[Category: Olucha, J.]]
[[Category: Olucha J]]
[[Category: Bacterial cytosol]]
[[Category: Class b flavin dependent n-hydroxylating monooxygenase]]
[[Category: N5-l-ornithine monooxygenase]]
[[Category: Ornithine hydroxylase]]
[[Category: Oxidoreductase]]
[[Category: Reduced form]]