3mji: Difference between revisions

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[[Image:3mji.png|left|200px]]


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==Activation of catalytic cysteine without a base in a Mutant Penicillin Acylase Precursor==
The line below this paragraph, containing "STRUCTURE_3mji", creates the "Structure Box" on the page.
<StructureSection load='3mji' size='340' side='right'caption='[[3mji]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3mji]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MJI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mji OCA], [https://pdbe.org/3mji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mji RCSB], [https://www.ebi.ac.uk/pdbsum/3mji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mji ProSAT]</span></td></tr>
{{STRUCTURE_3mji|  PDB=3mji  |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.


===Activation of catalytic cysteine without a base in a Mutant Penicillin Acylase Precursor===
==See Also==
 
*[[Penicillin acylase|Penicillin acylase]]
 
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_16508111}}
 
==About this Structure==
[[3mji]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJI OCA].
 
==Reference==
<ref group="xtra">PMID:016508111</ref><references group="xtra"/>
[[Category: Lysinibacillus sphaericus]]
[[Category: Lysinibacillus sphaericus]]
[[Category: Penicillin amidase]]
[[Category: Dodson GG]]
[[Category: Dodson, G G]]
[[Category: Murshudov GN]]
[[Category: Murshudov, G N.]]
[[Category: Pathak MC]]
[[Category: Pathak, M C.]]
[[Category: Suresh CG]]
[[Category: Suresh, C G.]]
[[Category: Amidase]]
[[Category: Antibiotic resistance]]
[[Category: Autoproteolysis]]
[[Category: Catalysis]]
[[Category: Hydrolase]]
[[Category: Penicillin]]
[[Category: Penicillin v acylase]]
[[Category: Zymogen]]