Multi-protein assemblies: Difference between revisions
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Many [[PDB file|PDB files]] contain [[Complexes|complexes]] in which a particular protein is interacting with a different protein in what are called [[Multi-protein assemblies|multi-protein assemblies]] or [[Multi-protein assemblies|multi-protein complexes]]. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes. | Many [[PDB file|PDB files]] contain [[Complexes|complexes]] in which a particular protein is interacting with a different protein in what are called [[Multi-protein assemblies|multi-protein assemblies]] or [[Multi-protein assemblies|multi-protein complexes]]. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes. | ||
==Examples== | |||
* [[Ribosome]] | |||
* [[Human Follicle-Stimulating Hormone Complexed with its Receptor]] | |||
* [[Platelet-receptor glycoprotein Ib alpha|Platelet-receptor glycoprotein Ib alpha bound to the von Willebrand Factor A1 Domain]] | |||
==See Also== | ==See Also== | ||
* [[Complexes]] | |||
* [[Complexes|Assemblies]] | |||
* [[Biological assembly|Biological unit]] | |||
* [[Biological assembly]] | |||
* [[Crystal contacts]] | * [[Crystal contacts]] | ||
* [[X-ray crystallography]] | * [[X-ray crystallography]] | ||
* [[Ligand]] | * [[Ligand]] | ||
== | |||
*[http://www-cryst.bioc.cam.ac.uk/~richard/piccolo/about.php PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions]. | ==External Resources== | ||
* [http://www-cryst.bioc.cam.ac.uk/~richard/piccolo/about.php PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions]. | |||
* [http://pir.georgetown.edu/pro/ PRO] provides an ontological representation of proteins in complexes. In particular, the authors are working to implement logical and consistent representation of protein complexes. | |||
*[https://www.molnac.unisa.it/BioTools/cocomaps/ COCOMAPS (bioCOmplexes COntact MAPS)] is a web server for analysis and visualization of the interfaces present in biological complexes, such as protein-protein, protein-DNA and protein-RNA complexes, making use of intermolecular contact maps. | |||
* [http://haddock.chem.uu.nl/ The HADDOCK web server] is web server for data-driven biomolecular docking for modeling of biomolecular complexes. | |||
==Literature Citations== | ==Literature Citations== | ||
Literature citations can also be found at the respective servers linked above. | |||
Literature citations | |||
