3t3n: Difference between revisions
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New page: '''Unreleased structure''' The entry 3t3n is ON HOLD Authors: Dorleans, A., de la Sierra-Gallay, I.L., Piton, J., Zig, L., Gilet, L., Putzer, H., Condon, C. Description: Molecular basi... |
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==Molecular basis for the recognition and cleavage of RNA (UUCCGU) by the bifunctional 5'-3' exo/endoribonuclease RNase J== | |||
<StructureSection load='3t3n' size='340' side='right'caption='[[3t3n]], [[Resolution|resolution]] 3.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3t3n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T3N FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.09Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t3n OCA], [https://pdbe.org/3t3n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t3n RCSB], [https://www.ebi.ac.uk/pdbsum/3t3n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t3n ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RNJ_THET2 RNJ_THET2] An RNase that has endonuclease and possibly 5'-3' exonuclease activity. Probably involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.<ref>PMID:18204464</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Thermus thermophilus HB27]] | |||
[[Category: Condon C]] | |||
[[Category: Dorleans A]] | |||
[[Category: Gilet L]] | |||
[[Category: Li de la Sierra-Gallay I]] | |||
[[Category: Piton J]] | |||
[[Category: Putzer H]] | |||
[[Category: Zig L]] | |||
