3t3o: Difference between revisions

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'''Unreleased structure'''


The entry 3t3o is ON HOLD
==Molecular basis for the recognition and cleavage of RNA (CUGG) by the bifunctional 5'-3' exo/endoribonuclease RNase J==
 
<StructureSection load='3t3o' size='340' side='right'caption='[[3t3o]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
Authors: Dorleans, A., de la Sierra-Gallay, I.L., Piton, J., Zig, L., Gilet, L., Putzer, H., Condon, C.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3t3o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T3O FirstGlance]. <br>
Description: Molecular basis for the recognition and cleavage of RNA (CUGG) by the bifunctional 5'-3' exo/endoribonuclease RNase J
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t3o OCA], [https://pdbe.org/3t3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t3o RCSB], [https://www.ebi.ac.uk/pdbsum/3t3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t3o ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNJ_THET2 RNJ_THET2] An RNase that has endonuclease and possibly 5'-3' exonuclease activity. Probably involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.<ref>PMID:18204464</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB27]]
[[Category: Condon C]]
[[Category: Dorleans A]]
[[Category: Gilet L]]
[[Category: Li de la Sierra-Gallay I]]
[[Category: Piton J]]
[[Category: Putzer H]]
[[Category: Zig L]]
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