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New page: left|200px<br /><applet load="2nyi" size="350" color="white" frame="true" align="right" spinBox="true" caption="2nyi, resolution 1.80Å" /> '''Crystal Structure of...
 
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[[Image:2nyi.jpg|left|200px]]<br /><applet load="2nyi" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2nyi, resolution 1.80&Aring;" />
'''Crystal Structure of an Unknown Protein from Galdieria sulphuraria'''<br />


==About this Structure==
==Crystal Structure of an Unknown Protein from Galdieria sulphuraria==
2NYI is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Galdieria_sulphuraria Galdieria sulphuraria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NYI OCA].  
<StructureSection load='2nyi' size='340' side='right'caption='[[2nyi]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2nyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Galdieria_sulphuraria Galdieria sulphuraria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NYI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nyi OCA], [https://pdbe.org/2nyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nyi RCSB], [https://www.ebi.ac.uk/pdbsum/2nyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nyi ProSAT], [https://www.topsan.org/Proteins/CESG/2nyi TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/J3QW32_GALSU J3QW32_GALSU]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ny/2nyi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nyi ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The ACT domain is a structurally conserved small molecule binding domain which is mostly involved in amino acid and purine metabolism. Here, we report the crystal structure of a tandem ACT domain-containing protein (ACTP) from Galdieria sulphuraria. The two ACTP monomers in the asymmetric unit form a dimer with a non-crystallographic twofold axis in a domain-swapped manner, showing a horseshoe-like structure with a central crevice. This structure contributes to expand our knowledge on the structural diversity of ACT domain-containing proteins. Proteins 2012; (c) 2012 Wiley Periodicals, Inc.
 
Crystal structure of tandem ACT domain-containing protein ACTP from Galdieria sulphuraria.,Bitto E, Kim do J, Bingman CA, Kim HJ, Han BW, Phillips GN Jr Proteins. 2012 Aug;80(8):2105-9. doi: 10.1002/prot.24101. Epub 2012 Jun 7. PMID:22528523<ref>PMID:22528523</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2nyi" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Galdieria sulphuraria]]
[[Category: Galdieria sulphuraria]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Bingman, C.A.]]
[[Category: Bingman CA]]
[[Category: Bitto, E.]]
[[Category: Bitto E]]
[[Category: CESG, Center.for.Eukaryotic.Structural.Genomics.]]
[[Category: McCoy JG]]
[[Category: Jr., G.N.Phillips.]]
[[Category: Phillips Jr GN]]
[[Category: McCoy, J.G.]]
[[Category: Wesenberg GE]]
[[Category: Wesenberg, G.E.]]
[[Category: center for eukaryotic structural genomics]]
[[Category: cesg]]
[[Category: protein structure initiative]]
[[Category: psi]]
 
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