3spu: Difference between revisions

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[[Image:3spu.jpg|left|200px]]


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==apo NDM-1 Crystal Structure==
The line below this paragraph, containing "STRUCTURE_3spu", creates the "Structure Box" on the page.
<StructureSection load='3spu' size='340' side='right'caption='[[3spu]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3spu]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3spu|  PDB=3spu  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spu OCA], [https://pdbe.org/3spu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spu RCSB], [https://www.ebi.ac.uk/pdbsum/3spu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.


===apo NDM-1 Crystal Structure===
==See Also==
 
*[[Beta-lactamase|Beta-lactamase]]
 
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
==About this Structure==
__TOC__
[[3spu]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPU OCA].
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
[[Category: King, D T.]]
[[Category: Large Structures]]
[[Category: Strynadka, N C.J.]]
[[Category: King DT]]
[[Category: Alpha beta/beta alpha sandwich]]
[[Category: Strynadka NCJ]]
[[Category: Beta lactam antibiotic]]
[[Category: Hydrolase]]
[[Category: Periplasmic space]]