3t7l: Difference between revisions
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New page: '''Unreleased structure''' The entry 3t7l is ON HOLD Authors: Chaikuad, A., Williams, E., Guo, K., Sanvitale, C., Berridge, G., Krojer, T., Muniz, J.R.C., Canning, P., Phillips, C., Shr... |
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==Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution== | |||
<StructureSection load='3t7l' size='340' side='right'caption='[[3t7l]], [[Resolution|resolution]] 1.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3t7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.09Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7l OCA], [https://pdbe.org/3t7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7l RCSB], [https://www.ebi.ac.uk/pdbsum/3t7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7l ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ZFY16_HUMAN ZFY16_HUMAN] May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.<ref>PMID:11546807</ref> <ref>PMID:14613930</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Berridge G]] | |||
[[Category: Bountra C]] | |||
[[Category: Bullock A]] | |||
[[Category: Canning P]] | |||
[[Category: Chaikuad A]] | |||
[[Category: Edwards AM]] | |||
[[Category: Guo K]] | |||
[[Category: Krojer T]] | |||
[[Category: Muniz JRC]] | |||
[[Category: Phillips C]] | |||
[[Category: Sanvitale C]] | |||
[[Category: Shrestha A]] | |||
[[Category: Weigelt J]] | |||
[[Category: Williams E]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 10:04, 1 March 2024
Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution
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