3t80: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 3t80 is ~~ON HOLD~~

==Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine==

== Structural highlights ==

<table><tr><td colspan='2'>[[3t80]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T80 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=3T80 FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTN:4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE'>CTN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=3t80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t80 OCA], [https://pdbe.org/3t80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t80 RCSB], [https://www.ebi.ac.uk/pdbsum/3t80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t80 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/ISPF_SALTY ISPF_SALTY] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]

~~Authors~~: ~~Seattle Structural Genomics Center for Infectious Disease (SSGCID), Staker, B~~.~~L.,~~ Edwards~~, T.E.~~

==See Also==

*[[MECDP synthase 3D structures|MECDP synthase 3D structures]]

~~Description~~: ~~Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine~~

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]

[[Category: Edwards TE]]

[[Category: Staker BL]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 3t80 is ON HOLD
+==Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine==
+<StructureSection load='3t80' size='340' side='right'caption='[[3t80]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3t80]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T80 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTN:4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE'>CTN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t80 OCA], [https://pdbe.org/3t80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t80 RCSB], [https://www.ebi.ac.uk/pdbsum/3t80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t80 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ISPF_SALTY ISPF_SALTY] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]
-Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID), Staker, B.L., Edwards, T.E.
+==See Also==
+*[[MECDP synthase 3D structures|MECDP synthase 3D structures]]
-Description: Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
+[[Category: Edwards TE]]
+[[Category: Staker BL]]