2p5u: Difference between revisions

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New page: left|200px<br /><applet load="2p5u" size="350" color="white" frame="true" align="right" spinBox="true" caption="2p5u, resolution 2.370Å" /> '''Crystal structure o...
 
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[[Image:2p5u.gif|left|200px]]<br /><applet load="2p5u" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2p5u, resolution 2.370&Aring;" />
'''Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD'''<br />


==About this Structure==
==Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD==
2P5U is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/UDP-glucose_4-epimerase UDP-glucose 4-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5U OCA].  
<StructureSection load='2p5u' size='340' side='right'caption='[[2p5u]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
[[Category: Single protein]]
== Structural highlights ==
[[Category: Thermus thermophilus]]
<table><tr><td colspan='2'>[[2p5u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P5U FirstGlance]. <br>
[[Category: UDP-glucose 4-epimerase]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37&#8491;</td></tr>
[[Category: Chen, L.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
[[Category: Chrzas, J.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p5u OCA], [https://pdbe.org/2p5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p5u RCSB], [https://www.ebi.ac.uk/pdbsum/2p5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p5u ProSAT], [https://www.topsan.org/Proteins/RSGI/2p5u TOPSAN]</span></td></tr>
[[Category: Dillard, B.]]
</table>
[[Category: Ebihara, A.]]
== Function ==
[[Category: Fu, Z-Q.]]
[https://www.uniprot.org/uniprot/Q5SKQ2_THET8 Q5SKQ2_THET8]  
[[Category: Kuramitsu, S.]]
== Evolutionary Conservation ==
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Rose, J.P.]]
Check<jmol>
[[Category: SECSG, Southeast.Collaboratory.for.Structural.Genomics.]]
  <jmolCheckbox>
[[Category: Shinkai, A.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p5/2p5u_consurf.spt"</scriptWhenChecked>
[[Category: Wang, B-C.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Yokoyama, S.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Zhao, M.]]
  </jmolCheckbox>
[[Category: NAD]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p5u ConSurf].
[[Category: national project on protein structural and functional analyses]]
<div style="clear:both"></div>
[[Category: nppsfa]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: secsg]]
[[Category: southeast collaboratory for structural genomics]]
[[Category: structural genomics]]
[[Category: thermus thermophilus hb8]]
[[Category: ttha0591]]
[[Category: udp-glucose 4-epimerase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 21:20:27 2008''
==See Also==
*[[UDP-galactose 4-epimerase|UDP-galactose 4-epimerase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB8]]
[[Category: Chen L]]
[[Category: Chrzas J]]
[[Category: Dillard B]]
[[Category: Ebihara A]]
[[Category: Fu Z-Q]]
[[Category: Kuramitsu S]]
[[Category: Rose JP]]
[[Category: Shinkai A]]
[[Category: Wang B-C]]
[[Category: Yokoyama S]]
[[Category: Zhao M]]

Latest revision as of 09:08, 21 February 2024

Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD

2p5u, resolution 2.37Å

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