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New page: left|200px<br /><applet load="2pbf" size="350" color="white" frame="true" align="right" spinBox="true" caption="2pbf, resolution 2.00Å" /> '''Crystal structure of...
 
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[[Image:2pbf.gif|left|200px]]<br /><applet load="2pbf" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2pbf, resolution 2.00&Aring;" />
'''Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine'''<br />


==About this Structure==
==Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine==
2PBF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7] with <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Protein-L-isoaspartate(D-aspartate)_O-methyltransferase Protein-L-isoaspartate(D-aspartate) O-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.77 2.1.1.77] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBF OCA].  
<StructureSection load='2pbf' size='340' side='right'caption='[[2pbf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Plasmodium falciparum 3d7]]
== Structural highlights ==
[[Category: Protein-L-isoaspartate(D-aspartate) O-methyltransferase]]
<table><tr><td colspan='2'>[[2pbf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PBF FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Arrowsmith, C.H.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
[[Category: Bochkarev, A.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pbf OCA], [https://pdbe.org/2pbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pbf RCSB], [https://www.ebi.ac.uk/pdbsum/2pbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pbf ProSAT]</span></td></tr>
[[Category: Edwards, A.M.]]
</table>
[[Category: Hassanali, A.]]
== Evolutionary Conservation ==
[[Category: Hui, R.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Kozieradzki, I.]]
Check<jmol>
[[Category: Lew, J.]]
  <jmolCheckbox>
[[Category: Lin, L.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pb/2pbf_consurf.spt"</scriptWhenChecked>
[[Category: Qiu, W.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Ravichandran, M.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: SGC, Structural.Genomics.Consortium.]]
  </jmolCheckbox>
[[Category: Sundstrom, M.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pbf ConSurf].
[[Category: Vedadi, M.]]
<div style="clear:both"></div>
[[Category: Wasney, G.]]
__TOC__
[[Category: Weigelt, J.]]
</StructureSection>
[[Category: Wernimont, A.K.]]
[[Category: Large Structures]]
[[Category: Zhao, Y.]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: SAH]]
[[Category: Arrowsmith CH]]
[[Category: isoaspartyl formation]]
[[Category: Bochkarev A]]
[[Category: methyltransferase]]
[[Category: Edwards AM]]
[[Category: p. falciparum]]
[[Category: Hassanali A]]
[[Category: protein repair]]
[[Category: Hui R]]
[[Category: sgc]]
[[Category: Kozieradzki I]]
[[Category: structural genomics consortium]]
[[Category: Lew J]]
 
[[Category: Lin L]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 21:22:03 2008''
[[Category: Qiu W]]
[[Category: Ravichandran M]]
[[Category: Sundstrom M]]
[[Category: Vedadi M]]
[[Category: Wasney G]]
[[Category: Weigelt J]]
[[Category: Wernimont AK]]
[[Category: Zhao Y]]
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