3srk: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase== | |||
<StructureSection load='3srk' size='340' side='right'caption='[[3srk]], [[Resolution|resolution]] 2.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3srk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SRK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LSA:1,2-BENZISOTHIAZOL-3(2H)-ONE+1,1-DIOXIDE'>LSA</scene>, <scene name='pdbligand=PTK:PYRENE-1,3,6,8-TETRASULFONIC+ACID'>PTK</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3srk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3srk OCA], [https://pdbe.org/3srk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3srk RCSB], [https://www.ebi.ac.uk/pdbsum/3srk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3srk ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KPYK_LEIME KPYK_LEIME] | |||
==See Also== | |||
*[[Pyruvate kinase 3D structures|Pyruvate kinase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Leishmania mexicana]] | |||
[[Category: Auld DS]] | |||
[[Category: Blackburn EA]] | |||
[[Category: Boxer M]] | |||
[[Category: Fothergill-Gilmore LA]] | |||
[[Category: McNae IW]] | |||
[[Category: Michels PAM]] | |||
[[Category: Morgan HP]] | |||
[[Category: Shen M]] | |||
[[Category: Walkinshaw MD]] | |||
[[Category: Walsh M]] | |||
[[Category: Wear MA]] | |||
Latest revision as of 06:10, 17 October 2024
A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase
| ||||||||||||
