3t06: Difference between revisions

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[[Image:3t06.png|left|200px]]


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==Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA==
The line below this paragraph, containing "STRUCTURE_3t06", creates the "Structure Box" on the page.
<StructureSection load='3t06' size='340' side='right'caption='[[3t06]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3t06]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T06 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.84&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t06 OCA], [https://pdbe.org/3t06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t06 RCSB], [https://www.ebi.ac.uk/pdbsum/3t06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t06 ProSAT]</span></td></tr>
{{STRUCTURE_3t06|  PDB=3t06  |  SCENE=  }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARHGB_HUMAN ARHGB_HUMAN] May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.


===Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA===
==See Also==
 
*[[Rho GTPase 3D structures|Rho GTPase 3D structures]]
 
*[[Rho guanine nucleotide exchange factor 3D structures|Rho guanine nucleotide exchange factor 3D structures]]
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</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 21816819 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21816819}}
 
==About this Structure==
[[3t06]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T06 OCA].
 
==Reference==
<ref group="xtra">PMID:021816819</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bielnicki, J A.]]
[[Category: Large Structures]]
[[Category: Derewenda, U.]]
[[Category: Bielnicki JA]]
[[Category: Derewenda, Z S.]]
[[Category: Derewenda U]]
[[Category: Dh-ph rhoa complex]]
[[Category: Derewenda ZS]]
[[Category: Guanine nucleotide exchange factor]]
[[Category: Pdzrhogef]]
[[Category: Rhoa]]
[[Category: Signaling protein]]
Retrieved from "https://proteopedia.org/3t06"