351d: Difference between revisions

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New page: left|200px<br /><applet load="351d" size="350" color="white" frame="true" align="right" spinBox="true" caption="351d, resolution 1.640Å" /> '''X-RAY CRYSTAL STRUC...
 
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[[Image:351d.gif|left|200px]]<br /><applet load="351d" size="350" color="white" frame="true" align="right" spinBox="true"
caption="351d, resolution 1.640&Aring;" />
'''X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE'''<br />


==Overview==
==X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE==
Hexammine ions are strong inducers of the transition from the B-form to, the left-handed Z-form in DNA. Here the structure of d(CACGCG). d(CGCGTG), obtained from crystals grown from a drop containing [Ru(NH3)6]Cl3 is, reported. The structure is clearly characterized as Z-DNA. When compared, with the structure of d(CACGCG).d(CGCGTG)/MgCl2 and that of d(CGCGCG)2, subtle differences are seen, most noticeably in the water structure. Since, stable well diffracting crystals grow easily in the presence of, [Ru(NH3)6]Cl3 and since this ion is not visible in the electron density it, is concluded that the ion plays a non-specific role in stabilizing Z-DNA.
<StructureSection load='351d' size='340' side='right'caption='[[351d]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[351d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=351D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=351D FirstGlance]. <br>
351D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=351D OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=351d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=351d OCA], [https://pdbe.org/351d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=351d RCSB], [https://www.ebi.ac.uk/pdbsum/351d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=351d ProSAT]</span></td></tr>
==Reference==
</table>
Structure of d(CACGCG).d(CGCGTG) in crystals grown in the presence of ruthenium III hexammine chloride., Karthe P, Gautham N, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):501-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761846 9761846]
__TOC__
[[Category: Protein complex]]
</StructureSection>
[[Category: Gautham, N.]]
[[Category: Large Structures]]
[[Category: Karthe, P.]]
[[Category: Gautham N]]
[[Category: double helix]]
[[Category: Karthe P]]
[[Category: z-dna]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 21:36:16 2008''

Latest revision as of 08:39, 7 February 2024

X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE

351d, resolution 1.64Å

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