Response regulator: Difference between revisions

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~~{{STRUCTURE_1zg1| PDB~~=~~1zg1 | SIZE~~=~~400| SCENE~~= |right~~|CAPTION~~=Se-Met ~~''E. coli''~~ response regulator ~~NarL~~ complex with ~~DNA and sulfate~~, [[~~1zg1~~]] }}

'''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments.

Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal ~~shich~~ is the signal receiving domain and C terminal which is the DNA-binding domain.

Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal which is the signal receiving domain and C terminal which is the DNA-binding domain (DBD).

*'''RR CheY''' is a chemotaxis response regulator in bacteria see [[Chemotaxis protein]].<ref>PMID:14563873</ref>.

*'''RR Spo0''' is the sporulation response regulator<ref>PMID:12829280</ref>.

*'''RR PleD''' is required in loss of motility<ref>PMID:7592388</ref>. For details see [[PleD activation]], [[PleD allosteric product inhibition]], [[PleD catalysis]] and [[Response regulator PLED in complex with C-di-GMP]]

*'''RR PhoP''' is important for survival under conditions of macrophage-induced stress<ref>PMID:21634789</ref>. For details see [[PhoP Regulatory Domain]] and [[PhoP-PhoQ]]

*'''Photosynthetic apparatus RR''' in ''Rhodobacter sphaeroides'' is involved in the transduction of signals which monitor oxygen levels. <ref>PMID:8955382</ref>. For details see [[PrrA in Rhodobacter sphaeroides]]

*'''RR WspR''' couples the chemosensory Wsp pathway to the overproduction of acetylated cellulase <ref>PMID:17379708</ref>. For details see [[WspR]].

*'''Redox RR''' is DNA-sequence specific. It controls transcription as a result of its phosphorylation by a redox sensor<ref>PMID:8405457</ref>.

~~{{TOC limit|limit=2}}~~

For '''iron response regulator Irr''' see [[Irr]].

== 3D Structures of response regulator ==

[[Response regulator 3D structure]]

</StructureSection>

== References ==

[[Category:Topic Page]]

Response regulator: Difference between revisions

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_1zg1|  PDB=1zg1  | SIZE=400| SCENE= |right|CAPTION=Se-Met ''E. coli'' response regulator NarL complex with DNA and sulfate, [[1zg1]] }}
+<StructureSection load='1kgs' size='350' side='right' scene='' caption='Se-Met DNA-binding response regulator D complex with thiocyanate, [[1kgs]]'>
 '''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments.
-Two-component RR is a complex of histidine kinase (sensor protein SP) and RR.  The RR act as phosphorylation-activated switches.  Most RR consist of N terminal shich is the signal receiving domain and C terminal which is the DNA-binding domain.
+Two-component RR is a complex of histidine kinase (sensor protein SP) and RR.  The RR act as phosphorylation-activated switches.  Most RR consist of N terminal which is the signal receiving domain and C terminal which is the DNA-binding domain (DBD).
+*'''RR CheY''' is a chemotaxis  response regulator in bacteria see [[Chemotaxis protein]].<ref>PMID:14563873</ref>. <br />
+*'''RR Spo0''' is the sporulation response regulator<ref>PMID:12829280</ref>. <br />
+*'''RR PleD''' is required in loss of motility<ref>PMID:7592388</ref>. For details see [[PleD activation]], [[PleD allosteric product inhibition]], [[PleD catalysis]] and [[Response regulator PLED in complex with C-di-GMP]]<br />
+*'''RR PhoP''' is important for survival under conditions of macrophage-induced stress<ref>PMID:21634789</ref>. For details see [[PhoP Regulatory Domain]] and [[PhoP-PhoQ]]<br />
+*'''Photosynthetic apparatus RR''' in ''Rhodobacter sphaeroides'' is involved in the transduction of signals which monitor oxygen levels.  <ref>PMID:8955382</ref>. For details see [[PrrA in Rhodobacter sphaeroides]] <br />
+*'''RR WspR''' couples the chemosensory Wsp pathway to the overproduction of acetylated cellulase <ref>PMID:17379708</ref>. For details see [[WspR]].<br />
+*'''Redox RR''' is DNA-sequence specific.  It controls transcription as a result of its phosphorylation by a redox sensor<ref>PMID:8405457</ref>. <br />
-{{TOC limit|limit=2}}
+For '''iron response regulator Irr''' see [[Irr]].
 == 3D Structures of response regulator ==
+[[Response regulator 3D structure]]
+</StructureSection>
+== References ==
+<references/>
 [[Category:Topic Page]]