2yc5: Difference between revisions

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[[Image:2yc5.jpg|left|200px]]


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==Inhibitors of the herbicidal target IspD==
The line below this paragraph, containing "STRUCTURE_2yc5", creates the "Structure Box" on the page.
<StructureSection load='2yc5' size='340' side='right'caption='[[2yc5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2yc5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YC5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YC5 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6BC:5-CHLORO-7-HYDROXY-6-(PHENYLMETHYL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE'>6BC</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2yc5|  PDB=2yc5  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yc5 OCA], [https://pdbe.org/2yc5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yc5 RCSB], [https://www.ebi.ac.uk/pdbsum/2yc5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yc5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ISPD_ARATH ISPD_ARATH] Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Is essential for chloroplast development and required for pigments and gibberellins biosynthesis.<ref>PMID:10841550</ref> <ref>PMID:12029484</ref> <ref>PMID:18236010</ref>


===INHIBITORS OF THE HERBICIDAL TARGET ISPD===
==See Also==
 
*[[MEP cytidylyltransferase 3D structures|MEP cytidylyltransferase 3D structures]]
 
== References ==
==About this Structure==
<references/>
[[2yc5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YC5 OCA].
__TOC__
 
</StructureSection>
==Reference==
<ref group="xtra">PMID:021766403</ref><ref group="xtra">PMID:016478479</ref><references group="xtra"/>
[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Hoeffken, H W.]]
[[Category: Large Structures]]
[[Category: Allosteric pocket]]
[[Category: Hoeffken HW]]
[[Category: Herbicide]]
[[Category: Non-mevalonate-pathway]]
[[Category: Transferase]]

Latest revision as of 10:49, 20 December 2023

Inhibitors of the herbicidal target IspD

2yc5, resolution 1.60Å

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