3tcx: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation== | |||
<StructureSection load='3tcx' size='340' side='right'caption='[[3tcx]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3tcx]] is a 28 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TCX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6Å</td></tr> | |||
--> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tcx OCA], [https://pdbe.org/3tcx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tcx RCSB], [https://www.ebi.ac.uk/pdbsum/3tcx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tcx ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. | |||
== | ==See Also== | ||
*[[Integrin 3D structures|Integrin 3D structures]] | |||
*[[Intercellular adhesion molecule|Intercellular adhesion molecule]] | |||
__TOC__ | |||
[[ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Boonyaleepun | [[Category: Large Structures]] | ||
[[Category: Gu | [[Category: Boonyaleepun V]] | ||
[[Category: Jin | [[Category: Gu X]] | ||
[[Category: Kang | [[Category: Jin MM]] | ||
[[Category: Kim | [[Category: Kang S]] | ||
[[Category: Mao | [[Category: Kim CU]] | ||
[[Category: Owens | [[Category: Mao Y]] | ||
[[Category: Owens RM]] | |||
[[Category: Springer | [[Category: Springer TA]] | ||
[[Category: | [[Category: Van Rijn SJ]] | ||
Latest revision as of 10:28, 6 November 2024
Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation
| ||||||||||||
