3gn2: Difference between revisions

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[[Image:3gn2.png|left|200px]]


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==Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00066730)==
The line below this paragraph, containing "STRUCTURE_3gn2", creates the "Structure Box" on the page.
<StructureSection load='3gn2' size='340' side='right'caption='[[3gn2]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3gn2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GN2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=AX8:1-(3,4-DICHLOROBENZYL)-1H-BENZIMIDAZOL-2-AMINE'>AX8</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
{{STRUCTURE_3gn2| PDB=3gn2 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gn2 OCA], [https://pdbe.org/3gn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gn2 RCSB], [https://www.ebi.ac.uk/pdbsum/3gn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gn2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O76290_TRYBB O76290_TRYBB]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/3gn2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gn2 ConSurf].
<div style="clear:both"></div>


===Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00066730)===
==See Also==
 
*[[Pteridine reductase|Pteridine reductase]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_19527033}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 19527033 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_19527033}}
 
==About this Structure==
[[3gn2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GN2 OCA].
 
==Reference==
<ref group="xtra">PMID:019527033</ref><references group="xtra"/>
[[Category: Trypanosoma brucei brucei]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Brenk, R.]]
[[Category: Brenk R]]
[[Category: Hunter, W N.]]
[[Category: Hunter WN]]
[[Category: Tulloch, L B.]]
[[Category: Tulloch LB]]
[[Category: Inhibitor]]
[[Category: Oxidoreductase]]
[[Category: Pteridine reductase]]
[[Category: Ptr1]]
[[Category: Short chain dehydrogenase]]
[[Category: Trypanosoma brucei]]

Latest revision as of 09:55, 21 February 2024

Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00066730)

3gn2, resolution 1.60Å

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