3r0i: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3r0i.jpg|left|200px]]


<!--
==IspC in complex with an N-methyl-substituted hydroxamic acid==
The line below this paragraph, containing "STRUCTURE_3r0i", creates the "Structure Box" on the page.
<StructureSection load='3r0i' size='340' side='right'caption='[[3r0i]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3r0i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R0I FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C0K:{(1S)-1-(3,4-DIFLUOROPHENYL)-4-[HYDROXY(METHYL)AMINO]-4-OXOBUTYL}PHOSPHONIC+ACID'>C0K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
{{STRUCTURE_3r0i|  PDB=3r0i  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r0i OCA], [https://pdbe.org/3r0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r0i RCSB], [https://www.ebi.ac.uk/pdbsum/3r0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r0i ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DXR_ECOLI DXR_ECOLI] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).[HAMAP-Rule:MF_00183]


===IspC in complex with an N-methyl-substituted hydroxamic acid===
==See Also==
 
*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_21866890}}, adds the Publication Abstract to the page
[[Category: Escherichia coli K-12]]
(as it appears on PubMed at http://www.pubmed.gov), where 21866890 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Bacher A]]
{{ABSTRACT_PUBMED_21866890}}
[[Category: Behrendt CT]]
 
[[Category: Eisenreich W]]
==About this Structure==
[[Category: Fischer M]]
[[3r0i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R0I OCA].
[[Category: Graewert T]]
 
[[Category: Groll M]]
==Reference==
[[Category: Illarionov B]]
<ref group="xtra">PMID:021866890</ref><references group="xtra"/>
[[Category: Illarionova V]]
[[Category: 1-deoxy-D-xylulose-5-phosphate reductoisomerase]]
[[Category: Kunfermann A]]
[[Category: Escherichia coli k-12]]
[[Category: Kurz T]]
[[Category: Bacher, A.]]
[[Category: Maes L]]
[[Category: Behrendt, C T.]]
[[Category: Matheeussen A]]
[[Category: Eisenreich, W.]]
[[Category: Pein MK]]
[[Category: Fischer, M.]]
[[Category: Graewert, T.]]
[[Category: Groll, M.]]
[[Category: Illarionov, B.]]
[[Category: Illarionova, V.]]
[[Category: Kunfermann, A.]]
[[Category: Kurz, T.]]
[[Category: Maes, L.]]
[[Category: Matheeussen, A.]]
[[Category: Pein, M K.]]
[[Category: Antimalarial agent]]
[[Category: Cytosol]]
[[Category: Inhibitor]]
[[Category: ISPC]]
[[Category: Mn]]
[[Category: Nadph]]
[[Category: Non-mevalonate pathway]]
[[Category: Oxidoreductase-antibiotic complex]]
[[Category: Reductoisomerase of desoxy-xylulose-5p to methyl-erythritol-3p]]
[[Category: Reverse hydroxamic acid ligand binding]]
[[Category: Rossmann fold]]

Latest revision as of 12:05, 14 March 2024

IspC in complex with an N-methyl-substituted hydroxamic acid

3r0i, resolution 2.10Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=3r0i&oldid=4096239"