3qf3: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3qf3.jpg|left|200px]]


<!--
==Crystal structure of EspR transcription factor from mycobacterium tuberculosis==
The line below this paragraph, containing "STRUCTURE_3qf3", creates the "Structure Box" on the page.
<StructureSection load='3qf3' size='340' side='right'caption='[[3qf3]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3qf3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QF3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LMR:(2S)-2-HYDROXYBUTANEDIOIC+ACID'>LMR</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene></td></tr>
{{STRUCTURE_3qf3|  PDB=3qf3  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qf3 OCA], [https://pdbe.org/3qf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qf3 RCSB], [https://www.ebi.ac.uk/pdbsum/3qf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qf3 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of EspR transcription factor from mycobacterium tuberculosis===
== Function ==
 
[https://www.uniprot.org/uniprot/ESPR_MYCTU ESPR_MYCTU] Virulence regulator that has both architectural and regulatory roles. Impacts cell wall functions and pathogenesis through regulation of multiple genes, including the espACD operon, which is a key ESX-1 component. Influences target gene expression positively or negatively, depending on its binding position relative to the genes it controls. Acts by binding directly to the DNA. May play a central role in regulating virulence gene expression.<ref>PMID:18685700</ref> <ref>PMID:22389481</ref> <ref>PMID:22479184</ref> <ref>PMID:21883526</ref>
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_21883526}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 21883526 is the PubMed ID number.
</StructureSection>
-->
[[Category: Large Structures]]
{{ABSTRACT_PUBMED_21883526}}
 
==About this Structure==
[[3qf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QF3 OCA].  
 
==Reference==
<ref group="xtra">PMID:021883526</ref><references group="xtra"/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Blasco, B.]]
[[Category: Blasco B]]
[[Category: Cole, S T.]]
[[Category: Cole ST]]
[[Category: Pojer, F.]]
[[Category: Pojer F]]
[[Category: C-terminal dimerization domain]]
[[Category: Homodimer]]
[[Category: N-terminal hth motif]]
[[Category: Transcription]]
[[Category: Transcription factor]]
Retrieved from "https://proteopedia.org/3qf3"