Clathrin: Difference between revisions

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{{STRUCTURE_3lvg|  PDB=3lvg | SIZE=400| SCENE= |right|CAPTION=Bovine clathrin heavy and light chains, [[3lvg]] }}
<StructureSection load='3lvg' size='350' side='right' caption='Bovine clathrin heavy (darkmagenta, magenta, violet) and light (yellow, green, cyan) chains (PDB entry [[3lvg]])' scene='46/465441/Cv/1'>


'''Clathrin''' (CLT) is a component of vescicle coast.  It is composed of 3 heavy chains (Hc) and 3 light chains (Lc) interacting in their C-termini and forming a triskelion.  The Hc domains are: N-terminal, ankle, distal leg, knee, proximal leg and trimerization.
'''Clathrin''' (CLT) is a component of vesicle coats.<ref>PMID:1063406</ref> For details see [[Clathrin JMU]].


{{TOC limit|limit=2}}
== Structural highlights ==


== 3D Structures of Clathrin ==
Clathrin is composed of <scene name='46/465441/Cv/2'>3 heavy chains (Hc) and 3 light chains (Lc) interacting in their C-termini and forming a triskelion</scene>. <ref>PMID:20493816</ref> The Hc domains are: N-terminal, ankle, distal leg, knee, proximal leg and trimerization.


[[1bpo]] – rCLT Hc N terminal domain + linker – rat<br />
[[FirstGlance/Virus_Capsids_and_Other_Large_Assemblies#Clathrin_Coat|Clathrin Coat]] shows a small, empty clathrin coat assembly of triskelions from an electron microscopic structure, [[3iyv]].
[[1b89]] – bCLT Hc proximal leg – bovine<br />
[[3lvg]] - bCLT Hc + Lc<br />
[[3lvh]] - bCLT Hc HUB fragment + Lc <br />
[[1xi4]], [[3iyv]] – bCLT Hc + Lc – Cryo EM


===Clathrin binary complexes===
== 3D Structures of Clathrin ==
[[Clathrin 3D structures]]


[[1c9i]], [[1c9l]] - rCLT Hc N terminal + B-adaptin 3<br />
</StructureSection>
[[2xzg]], [[2xzh ]]- CLT Hc N terminal + pitstop inhibitor - human<br />
[[1utc]] - bCLT Hc N terminal + amphiphysin peptide<br />
[[1xi5]] - bCLT Hc + auxilin J-domain – Cryo EM<br />
[[3gc3]] – bCLT Hc WD domain + b-arrestin-1<br />
[[3gd1]] - bCLT Hc + Hc WD domain + b-arrest


== References ==
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]
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