3tem: Difference between revisions

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[[Image:3tem.jpg|left|200px]]


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==Quinone Oxidoreductase (NQ02) bound to the imidazoacridin-6-one 6a1==
The line below this paragraph, containing "STRUCTURE_3tem", creates the "Structure Box" on the page.
<StructureSection load='3tem' size='340' side='right'caption='[[3tem]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3tem]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TEM FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6A1:HYDROXY(2-{[(5S)-6-HYDROXY-8-METHOXY-4,5-DIHYDRO-3H-IMIDAZO[4,5,1-DE]ACRIDIN-5-YL]AMINO}ETHYL)DIMETHYLAMMONIUM'>6A1</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3tem|  PDB=3tem  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tem OCA], [https://pdbe.org/3tem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tem RCSB], [https://www.ebi.ac.uk/pdbsum/3tem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tem ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>


===Quinone Oxidoreductase (NQ02) bound to the imidazoacridin-6-one 6a1===
==See Also==
 
*[[Quinone reductase 3D structures|Quinone reductase 3D structures]]
 
== References ==
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<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_21859103}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 21859103 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_21859103}}
 
==About this Structure==
[[3tem]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEM OCA].
 
==Reference==
<ref group="xtra">PMID:021859103</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Dunstan, M S.]]
[[Category: Large Structures]]
[[Category: Leys, D.]]
[[Category: Dunstan MS]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Leys D]]

Latest revision as of 10:08, 1 March 2024

Quinone Oxidoreductase (NQ02) bound to the imidazoacridin-6-one 6a1

3tem, resolution 1.45Å

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