1dw9: Difference between revisions

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[[Image:1dw9.png|left|200px]]


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==Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site==
The line below this paragraph, containing "STRUCTURE_1dw9", creates the "Structure Box" on the page.
<StructureSection load='1dw9' size='340' side='right'caption='[[1dw9]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1dw9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DW9 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1dw9|  PDB=1dw9  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dw9 OCA], [https://pdbe.org/1dw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dw9 RCSB], [https://www.ebi.ac.uk/pdbsum/1dw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dw9 ProSAT], [https://www.topsan.org/Proteins/MCSG/1dw9 TOPSAN]</span></td></tr>
 
</table>
===STRUCTURE OF CYANASE REVEALS THAT A NOVEL DIMERIC AND DECAMERIC ARRANGEMENT OF SUBUNITS IS REQUIRED FOR FORMATION OF THE ENZYME ACTIVE SITE===
== Function ==
 
[https://www.uniprot.org/uniprot/CYNS_ECOLI CYNS_ECOLI] Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
 
== Evolutionary Conservation ==
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dw/1dw9_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_10801492}}
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==About this Structure==
  </jmolCheckbox>
[[1dw9]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DW9 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dw9 ConSurf].
 
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==Reference==
__TOC__
<ref group="xtra">PMID:010801492</ref><ref group="xtra">PMID:002822670</ref><ref group="xtra">PMID:003518792</ref><ref group="xtra">PMID:003651424</ref><ref group="xtra">PMID:006994799</ref><references group="xtra"/>
</StructureSection>
[[Category: Cyanase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Anderson, P M.]]
[[Category: Large Structures]]
[[Category: Joachimiak, A.]]
[[Category: Anderson PM]]
[[Category: Mcsg, Midwest Center for Structural Genomics.]]
[[Category: Joachimiak A]]
[[Category: Otwinowski, Z.]]
[[Category: Otwinowski Z]]
[[Category: Perrakis, A.]]
[[Category: Perrakis A]]
[[Category: Walsh, M A.]]
[[Category: Walsh MA]]
[[Category: Cyanate degradation]]
[[Category: Lyase]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]