3thj: Difference between revisions

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[[Image:3thj.png|left|200px]]


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==Crystal structure of the Co2+2-HAI-L-Orn complex==
The line below this paragraph, containing "STRUCTURE_3thj", creates the "Structure Box" on the page.
<StructureSection load='3thj' size='340' side='right'caption='[[3thj]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3thj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3THJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3THJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene></td></tr>
{{STRUCTURE_3thj|  PDB=3thj  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3thj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3thj OCA], [https://pdbe.org/3thj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3thj RCSB], [https://www.ebi.ac.uk/pdbsum/3thj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3thj ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/ARGI1_HUMAN ARGI1_HUMAN] Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:[https://omim.org/entry/207800 207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.<ref>PMID:1463019</ref> <ref>PMID:7649538</ref>  
== Function ==
[https://www.uniprot.org/uniprot/ARGI1_HUMAN ARGI1_HUMAN]


===Crystal structure of the Co2+2-HAI-L-Orn complex===
==See Also==
 
*[[Arginase 3D structures|Arginase 3D structures]]
 
== References ==
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<references/>
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__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 21870783 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_21870783}}
 
==About this Structure==
[[3thj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3THJ OCA].
 
==Reference==
<ref group="xtra">PMID:021870783</ref><references group="xtra"/>
[[Category: Arginase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Antonio, E L.D.]]
[[Category: Large Structures]]
[[Category: Christianson, D W.]]
[[Category: Christianson DW]]
[[Category: Arginase fold]]
[[Category: D'Antonio EL]]
[[Category: Hydrolase]]
Retrieved from "https://proteopedia.org/3thj"