3ozo: Difference between revisions

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[[Image:3ozo.jpg|left|200px]]


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==Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with NGT==
The line below this paragraph, containing "STRUCTURE_3ozo", creates the "Structure Box" on the page.
<StructureSection load='3ozo' size='340' side='right'caption='[[3ozo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ozo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ostrinia_furnacalis Ostrinia furnacalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OZO FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NGT:3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL'>NGT</scene></td></tr>
{{STRUCTURE_3ozo|  PDB=3ozo  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ozo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ozo OCA], [https://pdbe.org/3ozo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ozo RCSB], [https://www.ebi.ac.uk/pdbsum/3ozo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ozo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HEXC_OSTFU HEXC_OSTFU] Hydrolyzes one beta-GlcNAc unit at a time from the non-reducing ends of substrates, with a preference for shorter substrates. The 2-acetamido group and the beta-glycoside bond linkage in the substrate are required for its activity. Active with p-nitrophenyl (pNP)-beta-GlcNAc, pNP-beta-GalNAc and chitooligosaccharides (degree of polymerization from 2 to 6), but not with the complex N-glycan substrate (GlcNAcbeta-1,2Manalpha-1,6)(GlcNAcbeta-1,2Manalpha-1,3)Manbeta-1,4GlcNAcbeta-1,4GlcNAc-PA (GnGn-PA), pNP-alpha-GlcNAc or with the long polymer colloidal chitin. Involved in chitin catabolism (PubMed:18959754). Involved in the degradation of old cuticle during the pupation stage (PubMed:21106526).<ref>PMID:18959754</ref> <ref>PMID:21106526</ref>  


===Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with NGT===
==See Also==
 
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
 
*[[Beta-Hexosaminidase 3D structures|Beta-Hexosaminidase 3D structures]]
==About this Structure==
*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]]
[[3ozo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ostrinia_furnacalis Ostrinia furnacalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OZO OCA].
== References ==
[[Category: Beta-N-acetylhexosaminidase]]
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Ostrinia furnacalis]]
[[Category: Ostrinia furnacalis]]
[[Category: Liu, F.]]
[[Category: Liu F]]
[[Category: Liu, T.]]
[[Category: Liu T]]
[[Category: Shen, X.]]
[[Category: Shen X]]
[[Category: Yang, Q.]]
[[Category: Yang Q]]
[[Category: Zhang, H.]]
[[Category: Zhang H]]
[[Category: Beta-n-acetyl-d-hexosaminidase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
Retrieved from "https://proteopedia.org/3ozo"