3t5n: Difference between revisions
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The | ==1.8A crystal structure of Lassa virus nucleoprotein in complex with ssRNA== | ||
<StructureSection load='3t5n' size='340' side='right'caption='[[3t5n]], [[Resolution|resolution]] 1.79Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3t5n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mopeia_Lassa_virus_reassortant_29 Mopeia Lassa virus reassortant 29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T5N FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.787Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t5n OCA], [https://pdbe.org/3t5n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t5n RCSB], [https://www.ebi.ac.uk/pdbsum/3t5n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t5n ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q5S585_9VIRU Q5S585_9VIRU] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses (By similarity).[PIRNR:PIRNR004029] | |||
==See Also== | |||
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Mopeia Lassa virus reassortant 29]] | |||
[[Category: Hastie KM]] | |||
[[Category: King LB]] | |||
[[Category: Liu T]] | |||
[[Category: Ngo N]] | |||
[[Category: Saphire EO]] | |||
[[Category: Woods VL]] | |||
[[Category: Zandonatti MA]] | |||
[[Category: De la Torre JC]] | |||
Latest revision as of 10:03, 1 March 2024
1.8A crystal structure of Lassa virus nucleoprotein in complex with ssRNA
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