3u5u: Difference between revisions
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New page: '''Unreleased structure''' The entry 3u5u is ON HOLD Authors: Liqun Xia, Martin Ruppert, Meitian Wang, Santosh Panjikar, Leif Barleben, Chitra Rajendran, Haili Lin, Joachim Stoeckigt D... |
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==Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity== | |||
<StructureSection load='3u5u' size='340' side='right'caption='[[3u5u]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3u5u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U5U FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u5u OCA], [https://pdbe.org/3u5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u5u RCSB], [https://www.ebi.ac.uk/pdbsum/3u5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u5u ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RG1_RAUSE RG1_RAUSE] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the treatment of heart disorders.<ref>PMID:10975500</ref> | |||
==See Also== | |||
*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rauvolfia serpentina]] | |||
[[Category: Barleben L]] | |||
[[Category: Lin H]] | |||
[[Category: Panjikar S]] | |||
[[Category: Rajendran C]] | |||
[[Category: Ruppert M]] | |||
[[Category: Stoeckigt J]] | |||
[[Category: Wang M]] | |||
[[Category: Xia L]] | |||
Latest revision as of 08:38, 20 March 2024
Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
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